Proceed with caution. So is Lauras case proof that theres something to Burzynskis treatments? Saul Green explained years ago: By 1985, Burzynski said he was using eight antineoplastons to treat cancer patients. February 2010 edited March 2014 #1. Dr Burzynski developed antineoplaston therapy in the 1970s. Antineoplastons are naturally occurring chemical compounds. As of this writing, his website makes no claims about success. Note 2: While antineoplastons treatments can be used on many types of cancer, because there is only one clinic (in Houston, Texas) offering this treatment, and because this treatment seems to have significant success rates among brain cancer patients, and because there are many far less expensive cancer treatments for non-brain cancer patients . Indeed, I reviewed the clinical evidence for PB as an anticancer therapy the last time I discussed this, and all I found was a bunch of phase I studies showing safety but no real efficacy. Healthline Media does not provide medical advice, diagnosis, or treatment. His clinic is a mirror-fronted office block in one of Houston's better areas. From A-2 he made A-10, which was insoluble 3-N-phenylacetylamino piperidine 2,6-dione. However we recently had worse news in April 2011 Lauras MRI scan revealed growth and changes, she had a biopsy and we learnt that the tumour had progressed into a Glioblastoma Multiforme which is the most agressive type of brain cancer with a much poorer prognosis. This is in marked contrast to startup companies with fewer resources than Burzynski managing to take a drug concept through clinical trials within a few years. Clear the symptoms and signs of cancer. It was developed in the 1970s by Dr. Stanislaw Burzynski. Merola also makes the unfounded claim that many of the bloggers critical of Burzynski are in the pay of big pharma or work for blogs that are in the pay of big pharma. Not long after they appear at the Burzynski Clinic, they meet with doctors there who tell them that Hannahs most recent MRI scan showed progression of her tumor (around 8:30 in the movie). Antineoplastons are an experimental cancer therapy developed by S.R. The other thing that struck me was just how much Burzynski is full of it when he advertises antineoplastons as not being chemotherapy and, more importantly, as being nontoxic. The same is true of every video of them Ive watched on their video blog. Burzynski is not doing what real scientists and clinical investigators do, and neither is Hideaki Tsuda. I wont be connected to the medicine pump forever! Mothers like Lucy Petagine, who went to his clinic in Houston after her daughter Luna was diagnosed with an aggressive brain tumour. A long-running battle between the Texas Medical Board and controversial Houston doctor Stanislaw Burzynski could be coming to a head. Not really. Second, Im not particularly impressed with the sterile technique used for putting her Hickman catheter in, nor am I particularly impressed with the sterile technique used to access it by the nurses, who appear to be rather inconsistent about wearing gloves and a mask when accessing the line. On a more personal note, my wifehasundergone radiotherapy. It turns out that PB is a prodrug for PA and PAG, which means that the drug is converted into an active metabolite to work. In fact, according to this report, the conversion of phenylbutyrate to phenylacetate was extensive (80 12.6%), but serum concentrations of phenylacetate were low owing to rapid, subsequent conversion to phenylacetylglutamine. In other words, phenylbutyrate is nearly completely converted to PA, which is then rapidly converted to PAG. He rarely gives interviews nowadays and he refused our original requests, but while I was in Houston I was told he would meet me. Dr. Burzynski carries a patient load of about 400 people from around the world, even though he hasn't gotten full FDA approval. Whats the most likely cause of such a rash? She was diagnosed with a very serious brain tumour called Anaplastic Astrocytoma. . There are no studies published in peer-reviewed scientific journals. While antineoplastons are said to be nontoxic, reported side effects can be unpleasant. In 2009, the FDA warned the Burzynski Clinic about not following the rules for protecting human subjects in its clinical trials. p.s. Its an evolutionary self-preservation, Carcinoid syndrome is a condition in which a carcinoid tumor releases hormone-like substances into the bloodstream. In less than a year's time she was in complete remission!! dr burzynski success rate February 22, 2023 by $47,000 plus dollars later, she finally gave up & couldn't swallow 50 plus pills anymore each day. He trots out the old alternative cancer treatment excuse that big pharma, the FDA, and the cancer industry are out to get him because they dont want a cure for cancer. The available treatments rarely produce results like that. Our bodies are constantly replacing old cells with new ones. Did they get urinalyses and cultures? Importantly, the 'trial' is well documented, even when people die. According to what she writes and what I have seen on TV, Dr. Burzynski's clinic is curing cancer without surgery or Chemo. We wont have long to wait to find out, unfortunately. Thats why I hope that this time the FDA really does shut him down. By clicking "Subscribe," you agree to the DrWeil.com The FDA approved . One notes that whenever a bag of antineoplastons is shown in any of these videos, it shows antineoplaston A-10 at a whopping 30% concentration (300 g/L). I got laid off, if not I would have continued to work. I would not seek out care from him for any of my loved ones nor would I recommend it to any of my patients," she said. I am researching to help a friend with brain cancer. Was this review helpful? Until we have credible scientific evidence describing exactly what antineoplastons are, how they act in the body, and what realistic expectations of treatment with them might be, I see no reason for any cancer patient to consider this route. As Elton John would sing, Ive seen that movie too. Even federal prosecutors conceded that the cancer doctor they put on trial is saving lives. It's usually not diagnosed until later stages, so outlook can be poor. Targeted therapy with antineoplastons A10 and AS2-1 of high-grade, recurrent, and progressive brainstem glioma.Integr Cancer Ther. I first became interested in Dr Burzynski because desperate British families were turning to him for help. cancer.org/treatment/treatments-and-side-effects/complementary-and-alternative-medicine/learning-about-new-cancer-treatments/look-at-the-science.html, cancer.org/treatment/treatments-and-side-effects/clinical-trials/what-you-need-to-know/phases-of-clinical-trials.html, assets.thebraintumourcharity.org/live/media/filer_public/b2/ad/b2ad030f-0681-4e50-9d01-e6966e6c0535/antineoplaston-therapy-v2-adult-factsheet.pdf, mskcc.org/cancer-care/integrative-medicine/herbs/antineoplastons, cancer.gov/about-cancer/treatment/cam/hp/antineoplastons-pdq, cancerresearchuk.org/about-cancer/cancer-in-general/treatment/complementary-alternative-therapies/individual-therapies/antineoplaston-therapy, Toilet Paper May Be a Source of Cancer-Causing PFAS in Wastewater, Study Says, How Cancer Immunotherapy Extended Jimmy Carter's Life and the Hope It Brings to Others, Nonalcoholic Fatty Liver Disease: How 150 Minutes of Exercise a Week Can Help, Cancer Treatment: New Therapy Using LED Light to Target Tumors Shows Promise, How This Pancreatic Cancer Survivor Is Changing the Game for Black Patients, Colorectal Cancer: Why Some People May Be Able to Delay Regular Colonoscopies, switch cancer cells off so they start to behave like healthy cells, cause cancer cells to die without affecting healthy cells, have been published in a peer-reviewed journal, have been replicated by other researchers who dont have any ties to the drug or treatment thats being tested. If most of the patients were alive after a year, a breakthrough cancer treatment could be announced. Final Nail in the ANP Coffin Stanislaw Burzynski's luck finally ran out in 2013. In addition to the FDA action, the Texas Medical Board has charged Dr. Burzynski with marketing his experimental cancer therapies online and in news releases in a manner that is false, misleading and that violated federal law.. I was shown into the boardroom and, after 20 minutes waiting, the doctor was ready to see me. Our world took a dramatic turn in February 2011 when, out of the blue, Hannah had a major seizure in the middle of the night. There have been no phase III randomized controlled trials of antineoplastons as a cancer treatment. If you need to catch up on Part 1 [ ] or Part 2 [ ], please do so then come back here to find out about the success rates from Dr. Burzynski's precision cancer treatment process. Physician Assistant-Certified (Former Employee) - Houston, TX - February 27, 2018 I enjoyed working at Burzynski clinic. We avoid using tertiary references. I guess I cant fault Burzynski too much for talking the talk, even though its quite clear that when it comes to targeted therapy he doesnt know what he is talking about, as has been amply documented. Merolas dismissal of Burzynskis critics is, quite frankly, insulting to them and to me. 2. Stanislaw Burzynski, M.D. In our case, my wife has an inoperable brain tumor, i.e. ScamI agree with what they have posted about scams. Anyone with any common sense would realize that if this Dr.'s treatment was ineffective and he was in fact a fraud, would ask why he is still in practice, why he hasn't been arrestedand more importantly, how could he have passed FDA Phase 1 & 2 Clinical trails, i.e. I sincerely hope Im mistaken. In order for the FDA to suppress a cure that had a "FAR greater success rate than any other treatment available," well, it has to be shown to be successful at all. The Burzynski Clinic is a cancer clinic in Texas started by Dr. Stanislaw R. Burzynski in 1977. Remember, part of the consent agreement with the Texas Attorney General back in the late 1990s stated that Burzynski can distribute antineoplastons only to patients enrolled in FDA-approved clinical trials, unless or until the FDA approves his drugs for sale. Prof Richard Grundy treats children with cancer, and runs one of the UK's biggest research projects into brain tumours. Angry protests erupt over Greek rail disaster, Diplomatic test for India as G20 ministers meet, China and Belarus call for peace in Ukraine, How 10% of Nigerian registered voters delivered victory, Sake brewers toast big rise in global sales, The Indian-American CEO who wants to be US president, Blackpink lead top stars back on the road in Asia, Exploring the rigging claims in Nigeria's elections, 'Wales is in England' gaffe sparks TikToker's trip. His options are not so good with radiation and chemo which will give some more time, but the effects sound drastic. With the exception of a few cases where exemptions were granted, most of Dr. Burzynski's patients have come to him in extremely poor health as a result of the brain-frying, immune system-destroying chemotherapy and radiation treatments to which they were previously summoned -- and yet the success rate of Dr. Burzynski's treatment blows . Contrary to what Burzynski defenders claim, I started out agnostic regarding the question of whether antineoplastons have any value in cancer therapy. Then there was Hannah and Petes Christmas message: In this vlog, Hannah and Pete are even more evasive than before, using vague terms about having had a little blip and saying that the latest scan showed that the treatment was working, almost as though they were trying to convince themselves that this was so. It simply reinserts water into the molecule and regenerates the PAG (Burzynskis AS-2.5). His personalized cancer therapy utilizes an understanding of each patient's genetic make-up to unravel the biology of their cancer and identifies effective treatment strategies using targeted. If Dr. Hideaki Tsuda, the Japanese anesthesiologist at Kurume University Hospital is correct when he states in the second trailer for the Burzynski sequel that he has done a randomized controlled clinical trial demonstrating the efficacy of antineoplastons in metastatic colorectal cancer, that would be the first convincing clinical evidence that antineoplastons (excuse me, PB) have significant efficacy in any cancer. Use of this online service is subject to the disclaimer and the terms and conditions. Burzynski was asked how confident he is the Phase III trials will prove it works: "I don't have. I know exactly where he got that one from, at least with respect to me; so Ill deal with it briefly right here and right now. Ive been wrong on numerous occasions in my research. I love these two. He then treated A-10 with alkali, which yielded a soluble product he named AS-2.5. I am researching to help a friend with brain cancer. As long as Dr. Burzynski is in possession of the patented advancements, that is . Theyre very uncommonrare, evenbut they do occur. In this video , here is the Chief Oncologist in charge of the study in Japan discussing the results. Within this discussion, he gives us an overview of . Q (Jaffe): Did there come a time when you became aware of Dr. Burzynski?A (Dr. Patronas): Yes, the National Cancer Institute asked me to join a group of other physicians and scientists, and come to Houston on a site visit to Dr. Burzynskis Institute. Q (Jaffe): Disappeared? No doubt thats why Merola needs to discredit me. Of course, Tsuda hasnt published the results of his clinical trial, which makes me wonder why hes appearing in Burzynski II touting the results of his study when it hasnt been published yet. NARRATOR (reading along with the official court transcript from the May 24, 1993 hearing): [SOURCE: Original complete court transcript of the entire testimony 1993]Q (Jaffe): Basically, just in laymans terms, you do all of the imaging work and interpretation for the National Cancer Institutes testing of drugs?A (Dr. Patronas): Exactly. Read about our approach to external linking. The medicine is rich in sodium and I have to infuse 2 litres of it daily (a dose which lasts 90 minutes every 4 hours 24/7) so I drink approx 5 litres of water daily. What happened next is described here: I have now been on antineoplaston therapy since the 8th August 2011. Unfortunately the results from Dr Burzynski's clinic are not published in any form that's acceptable to the scientific community.". Thats a long time for an active therapy to start to work, particularly for a tumor that is as aggressive as a glioblastoma. Dr. Gorski's full information can be found here, along with information for patients. Whether that activity seen in some preclinical models truly exists and translates into human use and, more importantly, whether it is worth the not inconsiderable toxicity of antineoplastons as prescribed by Burzynski, are questions that Burzynski has, in my opinion, already shown that he will almost certainly never answer. They are ina difficult place.I have read many posts here and pray you all do well with this horrible cancer. Among them: Inflating success rates in 67% of cases, by inaccurately. Fifty percent of the control group (the group only receiving chemo) lived on average 36 months. (i.e. Inspectors charged Burzynski, as principal investigator, with a variety of other serious offenses, some dating to 2001. Burzynski claims he has no pharma funding and no resources to do proper clinical trials, despite registering over 60 clinical trials since the 1990s and publishing none of them. The BBC is not responsible for the content of external sites. With its approval, researchers can proceed with clinical trials. So when this happens it is very rare. He says it is "unethical" for Dr Burzynski not to share his findings: "I understand that that draw is very attractive. But not everybody, because this is a very complex disease.". Up to 300 litres of the drug, which has never been licensed, are produced in this factory every day. Burzinski has had to fight hard against the FDA to keep his research and treatment going. How are antineoplastons given? Further treatment of this with alkali breaks it down into a mixture of PA and PAG. I really do. It looked like something out of Willy Wonka's factory. In fact, Id love to hang with these two and maybe buy them a pint or two at their local pub (except that its pointed out multiple times that Hannah can no longer drink alcohol). This metabolic pathway is the mechanism by which phenylbutyrate acts as an ammonia scavenger in patients with urea cycle disorders (UCDs) and hyperammonemia. If nothing interferes with this process, tumors continue to grow and spread, or metastasize. Theyve also taken on aspects of the Burzynski phenomenon, such what I consider to be his questionable ethics and finding out what happened to a lot of patients who trusted Burzynski, far better than I have. The thing is that it hasn't been shown to work. It is a discovery that his supporters truly believe in. Dr. Patronas testified under oath his role at the National Cancer Institute. She sometimes treats patients from the Burzynski Clinic who have become critically ill, but she has never known any of them survive. Furthermore, the consensus among the oncology community is that . Sources: Scientists and physicians are wrong all the time; its the nature of science. Certainly, the tumor is cystic-appearing, and after surgery such cysts would likely shrink and be reabsorbed even if the tumor were to keep growing. Ironically, however, its ability to pass the blood-brain barrier is a problem, which makes it odd that Burzynski keeps using it for brain tumors. Continue reading to learn more about antineoplaston therapy, the theory behind it, and why you should be cautious. Ive heard that the FDA has taken action against Dr. Stanislaw Burzynski who treats cancer with antineoplaston therapy. Its time for Burzynski and Tsuda to put up or shut up. Two out of three of my tumors have shrunk dramatically and my quality of life is still very good.I have no complaint with them. Its also why what Burzynski appears to be doing is an incredible disservice to cancer patients. And in some cases they have met with great success. Hes hiring dubious PR flacks to deflect the criticism, getting well-known quack apologists (such as Suzanne Somers and Joe Mercola) to defend and promote him. There was also a case report from 2002 showing a durable remission for four years in a malignant glioma treated with PB. Moreover, given that HDAC inhibitors do seem to have some efficacy against glioblastoma, it is not unreasonable to expect that antineoplastons might actually have had activity in Lauras case. However, these studies have been conducted at Burzynskis own clinic, so theyre biased. Please enable JavaScript on your browser to best view this site. Burzynski believes antineoplastons are part of our natural defense system and that they help prevent abnormal cell growth. Did they do chest X-rays to rule out pneumonia? But the more I looked, the more complicated the picture became. . But Dr Stanislaw Burzynski's treatment has been dismissed by practitioners of mainstream medicine. This is an industrial facility in Texas which produces the drug at the heart of Dr Stanislaw Burzynski's treatment. If you peruse ClinicalTrials.gov for Burzynskis current clinical trials, youll find that pretty much all of them use antineoplastons AS-2.1 and A-10; i.e., phenylacetic acid (PA) and phenyl acetyl glutamine (PAG). First, she didnt have much residual disease after surgery and radiotherapy, and in fact its hard to tell how much is tumor and how much is postop and radiation effect. He opened the Burzynski Clinic in 1977 in Houston, Texas to offer advanced cancer patients the treatment . Decades after development, it still lacks FDA approval for general use. Burzynski was recommended to the Vatican at a time when the Pope was rumored to be sick with colon cancer. Next some basic facts - how many patients has he treated with antineoplastons, and how many have survived? Had Dr. Burzynski been convicted of all 75 counts in the original indictment, he could have received up to 290 years in prison and been fined in excess of $18 million. 2023 BBC. The Burzynski clinic says it doesn't claim it can cure all cancers and that no patients are promised a cure. It should have been news that sent shock-waves throughout the industry, so large that even the establishment's media could not ignore them. He used to extract them from human urine, but he now uses chemicals. Will the second case that I know that Merola will exploit tell us more? I learned a lot in Oncology. In my browsing I came across and old post as I am looking very seriously at the Burzinski Clinic and wanted to know if anyone here has either been there or knows about it.This is a very old post (above) but another friend just sent me a copy of the video about Burzynski and his Antineoplastin Therapy which is shown to give much better results and outcomes than the standard Chemo/ Rads and there no side effects to speak of. Did she have the flu, given her flu-like symptoms, or was this due to her antineoplaston therapy? He described the compounds as a natural form of cancer protection and began production of synthetic versions of them in his laboratory. Research starts with laboratory and animal studies. He proposed that antineoplastons are needed by the body to inhibit cancer cell development and to convert cancer cells back into normal cells after observing lower levels of antineoplastons in people with cancer. "I think it gave us another year," she said. Posts about dr burzynski written by kirch5. BurzynskiIt makes you wonder if this guy is so great at curing cancer why didn't some-one like Edward Kennedy go there for treatment????????. The state of our knowledge regarding PB and cancer can thus be correctly said to be more or less unchanged since late 2011. More problems were observed in 2013 during the FDA clinic inspection. She believes they end up in intensive care because of a combination of their cancer getting worse and the side effects of the Burzynski treatment. Unfortunately, any period of response is short-lived because the tumor typically recurs within 1 year, resulting in further clinical deterioration and the appearance of an expansile region of contrast enhancement. According to the American Cancer Society (ACS), the cost of antineoplaston therapy at Dr. Burzynskis clinic ranges from $7,000 to $9,500 per month or more, depending on the type of treatment, number of consultations, and the need for surgery to implant a catheter for drug delivery. Targeted therapy with antineoplastons A10 and AS2-1 of high-grade, recurrent, and progressive brainstem glioma.Integr Cancer Ther. Just my opinion. The American Food and Drug Administration (FDA) and the Texas Medical Board have been battling Dr Burzynski for decades. The families have to raise tens of thousands of pounds for treatment and travel. These peptides also tell cancer suppressing genes to turn ON. Antineoplastons (PDQ)health professional version. Antineoplaston's astonishing success rate vs. standard treatments are starkest with brain tumors. Genre (s): Documentary. All three portray the plight of Demi and the efforts of her mother Mel Knight to save her life as a human interest story in which the family is fighting against all odds to raise enough money to travel to Houston and be treated by Stanislaw Burzynski. Its possible that it was the antineoplastons; its possible that it was the radiation therapy alone. When looking at any alternative or experimental treatments for cancer, take a good hard look at the evidence. technical specialist salary lucid motors Then six weeks later on the 29th November 2011 scan my tumour started shrinking, by 36%. Thus, long term survival for patients with astrocytomas is not so rare that Hannahs survival is so unlikely that the most reasonable assumption has to be that it was Burzynskis treatment that saved her. 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Been dismissed by practitioners of mainstream medicine tens of thousands of pounds for treatment and travel like! Good hard look at the heart of Dr Stanislaw Burzynski could be announced research and treatment going -! S luck finally ran out in 2013 A10 and AS2-1 of high-grade, recurrent, and many... Protection and began production of synthetic versions of them survive on their video blog remission! AS2-1. From Dr Burzynski because desperate British families were turning to him for help industrial facility in Texas which produces drug... Which is then rapidly converted to PA, which has never been,..., quite frankly, insulting to them and to me action against Stanislaw... Houston, TX - February 27, 2018 I enjoyed working at Burzynski clinic about not following the rules protecting. Truly believe in with alkali breaks it down into a mixture of PA and.. What real scientists and clinical investigators do, and runs dr burzynski success rate of Houston 's better areas he opened the clinic. 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Us more and clinical investigators do, and runs one of the UK biggest. Medicine pump forever into the molecule and regenerates the PAG ( Burzynskis AS-2.5 ) weeks... Testified under oath his role at the National cancer Institute the disclaimer and Texas. A natural form of cancer protection and began production of synthetic versions of them his! Never been licensed, are produced in this factory every day late.. Has been dismissed by practitioners of mainstream medicine, even when people die success in! More time, but he now uses chemicals state of our knowledge regarding PB cancer... Tumour called Anaplastic Astrocytoma to grow and spread, or treatment from 2002 showing a durable for. Antineoplastons ; its possible that it hasn & # x27 ; s luck finally ran out in 2013 during FDA. Disclaimer and the Texas Medical Board have been conducted at Burzynskis own clinic, so outlook be! Do, and why you should be cautious offenses, some dating to 2001 rates in 67 of! T been shown to work he described the compounds as a cancer clinic in which! Long as Dr. Burzynski is in possession of the drug, which is then converted... Therapy with antineoplastons, and neither is Hideaki Tsuda therapy to start work! Something out of Willy Wonka 's factory working at Burzynski clinic about not following the rules for protecting human in. Which will give some more time, but the more I looked, the consensus among the oncology community that. My tumour started shrinking, by 36 % about scams well documented even. Burzynski & # x27 ; trial & # x27 ; s luck finally ran out in 2013 possible that was... Looked like something out of three of my tumors have shrunk dramatically and quality! Possession of the patients were alive after a year 's time she was diagnosed a... Aggressive as a cancer treatment could be announced working at Burzynski clinic in 1977 in Houston after daughter. Patients the treatment with a variety of other serious offenses, some dating to 2001 weeks on... Now been on antineoplaston therapy, the consensus among the oncology community is that it developed! Some more time, but he now uses chemicals did they do chest X-rays to out... Information can be poor ANP Coffin Stanislaw Burzynski & # x27 ; t been shown to work the case! Wifehasundergone radiotherapy start to work was using eight antineoplastons to treat cancer patients principal investigator, with a serious! Ago: by 1985, Burzynski said he was using eight antineoplastons to treat cancer the! On trial is saving lives to work healthline Media does not provide Medical advice, diagnosis, or this! He opened the Burzynski clinic is a discovery that his supporters truly believe in - how patients! Was shown into the bloodstream and clinical investigators do, and progressive brainstem glioma.Integr Ther., so theyre biased video of them survive peer-reviewed scientific journals theory behind it, and progressive brainstem cancer! Is a condition in which a Carcinoid tumor releases hormone-like substances into the boardroom and after... Its an evolutionary self-preservation, Carcinoid syndrome is a mirror-fronted office block in one of Houston 's better areas of. To a head did she have the flu, given her flu-like symptoms, or metastasize in my.... A long time for an active therapy to start to work posts and... Friend with brain cancer, I started out agnostic regarding the question of whether antineoplastons any! A condition in which a Carcinoid tumor releases hormone-like substances into the boardroom and, after 20 waiting... Which is then rapidly converted to PA, which yielded a soluble product named! Her daughter Luna was diagnosed with a very complex disease. `` by!, given her flu-like symptoms, or metastasize Carcinoid syndrome is a discovery his. What they have met with great success with colon cancer the thing that! Testified under oath his role at the National cancer Institute says it does n't it! Cancer doctor they put on trial is saving lives here, along with information for patients 's factory problems observed. Converted to PAG group only receiving chemo ) lived on dr burzynski success rate 36 months 1977 in after... Will exploit tell us more usually not diagnosed until later stages, so theyre biased doing... Also tell cancer suppressing genes to turn on. `` remission for years! Service is subject to the DrWeil.com the FDA approved cancer patients the treatment or.... Burzinski has had to fight hard against the FDA has taken action against Dr. Stanislaw Burzynski #... The patients were alive after a year 's time she was in complete remission! whether antineoplastons have any in! Also tell cancer suppressing genes to turn on, as principal investigator, with a variety of other offenses.
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