is benzonatate dangerous

As an oral antitussive agent, it acts by anesthetizing the pulmonary stretch receptors with a 1520-min onset of action for a duration of 38 h (7, 8, 21, 22). Available for Android and iOS devices. Benzonatate overdose can lead to life-threatening adverse events including seizures and cardiac arrhythmias. This material may not be published, broadcast, rewritten, or redistributed. Can be taken up to three times daily. Most drugs are good for at least one year past their dispense date. It is chemically related to medicines used as local anesthetics and works by numbing the nerves in the lungs which trigger a cough reflex. Pharmacists should dispense benzonatate in child-resistant containers. The FDA warning focused on accidental overdose in children under 10. Generally speaking, the contagiousness of RSV is slightly higher or comparable to other respiratory viruses. Also remember it helps to take this with a glass of water to help break up anything in your chest this is only a cough suppressant. Also problematic will be cases where a single crushed or broken benzonatate capsule may have caused laryngospasm or a similar hypersensitivity reaction in the oral cavity. Some of these side effects may result from chewing or. Portions of this document last updated: Feb. 01, 2023. We comply with the HONcode standard for trustworthy health information. (, Evans, M.S., Maglinger, G.B., Fletcher, A.M., Johnson, S.R. Not recommended during pregnancy; only use if benefits outweigh risks. Like other LAs, benzonatate is a potent voltage-gated sodium channel inhibitor, yet other unknown mechanisms may be at work (7, 10, 20). Interestingly, these ester-type LAs have generally fallen out of favor, in both the dental and the anesthesiology fields, for the amide-type LAs such as lidocaine and bupivacaine (15, 16). Non-allergic reactions vary from psychomotor responses to hypersensitivity reactions to other adverse events including dose-related toxicity. Benzonatate is available in 100 mg and 200 mg liquid-filled spherical capsules. Pfizer, Inc., Madison, NJ; Crouch, B.I., Knick, K.A., Crouch, D.J., Matsumura, K.S., Rollins, D.E. Is it okay to take propranolol past the expiration date on the bottle. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Tessalon [Package Insert]. Our website services, content, and products are for informational purposes only. Patients and caregivers should dispose of any leftover benzonatate in their household trash (see. Taken in overdose, benzonatate can rapidly cause seizures, cardiac arrhythmias and death. Dont take this drug again if youve ever had an allergic reaction to it. . Review/update the We comply with the HONcode standard for trustworthy health information. And if it is over a year old or more, is it safe to take. All possible dosages and drug forms may not be included here. How long does Benzonatate stay in your system? If a child accidentally ingests benzonatate, seek medical attention immediately. Still looking for answers? pug? However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Sucking or chewing the capsule may cause your mouth and throat to feel numb or cause other serious side effects. Swallow the pill whole. Keep it in your carry-on bag. The drug is not approved for children younger than 10 years old. You should refer to the prescribing information for benzonatate for a complete list of interactions. Benzonatate information for Healthcare Professionals. Is It Possible to Get RSV More Than Once? However, accidental or inappropriate use of the drug which comes in gel capsules, can lead to serious health problems, In children such as convulsions, cardiac arrest and death. Only take as directed. Be sure to avoid doing this when the weather is very hot or very cold. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If you are a Mayo Clinic patient, this could Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. In this case, 20 pills were missing from a prescription that did not belong to the decedent. Dr. Baggerman said it is ok to use the drug if its prescribed to you by a doctor and it works. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. LFTs require periodic surveillance. FDA encourages healthcare professionals to talk with their patients about this risk. The most common side effects of Benzonatate include: drowsiness, dizziness, headache, Overdose of benzonatate has been reported in adults and adolescents. If you take too much: You could have dangerous levels of the drug in your body. In addition, they can also have effects on the gastrointestinal (GI) system. Recognize the signs and symptoms of benzonatate overdose, which may include restlessness, tremors, convulsions, coma, and cardiac arrest. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Hope you get to feeling better soon if not by next week you should see your doctor. hallucinations (seeing or hearing something that isnt there). Fast-acting. describe fatalities in 20 of the 31 overdose cases reported to the FDA Adverse Event Reporting System (AERS), recognizing a rapid onset of symptoms (within 1 h) and a relatively low margin for safety (6). A class of drugs is a group of medications that work in a similar way. Two pediatric patients (ages 12 months and 4 years) were hospitalized due to accidental benzonatate ingestion and survived the event. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Even when most Pharmacies put the expiry date on the bottle the computer puts either 6 mo to the one-year expiration date on the bottle and the medication really has several years on the stock bottle we can shorten the date but of course, we can't make it longer. Be sure to tell your doctor about all medications, vitamins, or herbs youre taking. Benzonatate may cause various side . Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. It does not smell nor look bad and it has been in a dark cabinet. 2. A recently published report describes the case of a 37-year-old female patient who . A recent issue of The Medical Letter briefly highlighted an FDA warning about benzonatate. There are a variety of over-the-counter (OTC) and prescription medications of the morphinan opiate class that help alleviate this issue. other information we have about you. FDA is adding new information about accidental ingestion resulting in overdose and death in children below 10 years of age to the Warnings and Precautions sections of labeling for benzonatate products to make healthcare professionals aware of this safety issue. For children: This medication hasnt been studied and shouldnt be used in children younger than 10 years old. Benzonatate is a non-narcotic cough medicine. This may cause you to feel dizzy or faint. I don't feel sick either. Drug class: Antitussives. (, Understanding the Epidemic. information is beneficial, we may combine your email and website usage information with Swallow the capsule whole. 100 mg to 200 mg orally three times a day as needed for cough Signs and symptoms of overdose can occur rapidly after ingestion (within 15-20 minutes). Never suck or chew on a benzonatate capsule. Dosage of drugs is not considered in the study. He listens actively, observes keenly, encourages questions and always provides straight answers. Children should have their cough evaluated and this medication should not be used in children. Available for Android and iOS devices. Children over 10 years old can take benzonatate (Tessalon). Perhaps the reason for sparse literature data for benzonatate over-ingestion (29) is the inability to detect benzonatate and recognize the metabolites. generic drugs) are not considered. Safety AnnouncementAdditional Information for Patients and CaregiversAdditional Information for Healthcare ProfessionalsData Summary. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Benzonatate oral capsule can cause drowsiness as well as other side effects. Medicines that interact with benzonatate may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with benzonatate. Generic name: benzonatate [ben-ZOE-na-tate] Focusing solely on the n = 9 compound may not be effective in determining an exact concentration, nor will just the 9-ethoxy component be the sole contributor to the abundance of the BABA metabolite. Benzonatate [Package Insert]. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. It is chemically related to medicines used as local anesthetics and works by numbing the nerves in the lungs which trigger a cough reflex. Benzonatate is used to relieve coughs due to colds or influenza (flu). Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use benzonatate only for the indication prescribed. Thats sound advice, but even in adults benzonatate can cause a feeling of numbness in the chest, confusion, and visual hallucinations. Individuals who experience overdose of benzonatate may exhibit restlessness, tremors, convulsions, coma, and cardiac arrest. (. FDA Drug Safety Communication: Death resulting from overdose after accidental ingestion of Tessalon (benzonatate) by children under 10 years of age, The Medical Letter brief: Benzonatate Warning. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Take benzonatate exactly as prescribed by your doctor. Keep benzonatate in a child-resistant container and store it out of reach of children at all times. It is not known if benzonatate is distributed into breastmilk. It works by reducing the cough reflex in the lungs and air passages. Benzonatate relieves cough by acting directly on the lungs and the breathing passages. This makes you cough less after taking the drug. Benzonatate is used to relieve coughing. Major Pharmaceuticals. Follow all directions on your prescription label and read all medication guides or instruction sheets. This medication hasnt been studied and shouldnt be used in children younger than 10 years old. Take each dose with a full glass of water. Use cough drops or lozenges. The personalized, attentive healthcare you deserve Benzonatate: A Cough Suppressant So Dangerous, You'd Rather Just Cough http://circleplastics.co.uk/author/vicki/ Benzonatate is a cough suppressant available by prescription as a generic medication or under the brand Tessalon. Respiratory Syncytial Virus (RSV) Infection, Respiratory Syncytial Virus (RSV) Vaccine, What to Know About RSVs Seasonal Trends and Symptoms, What to know about Respiratory Syncytial Virus (RSV) Tests, The 8 Best Air Purifiers for Dust of 2023, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, Symptoms of a Collapsed Trachea and What They Mean. In some cases, they may not be available in every strength or form as the brand-name version. include protected health information. Benzonatate is a drug, which works by numbing the throat and lungs, prescribed to treat coughs that are unresponsive to over-the-counter cough medicines. This switch has been partially attributed to allergies associated with their particular metabolites. Important legal mumbo jumbo: Accidental death has occurred in children under 10 years old. Benzonatate should not be given to kids under 10 years of age," said Eric Baggerman, Pediatrician at Amistad Community health center. Deaths in children have been reported within hours of the accidental ingestion. This drug should be used only if the potential benefit justifies the potential risk to the fetus. The safety and effectiveness of benzonatate in children under 10 years of age have not been established. Keep out of reach of children. Benzonatate oral capsule can cause drowsiness as well as other side effects. 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A narrow safety margin for benzonatate has been demonstrated by overdose case studies (13, 20, 22, 24). The study uses data from the FDA. If the patient chews or sucks the liquid-filled capsules or "softgels", the drug can cause laryngospasm, bronchospasm and circulatory collapse. Benzonatate works by numbing the throat and lungs, making the cough reflex less active. Generally well tolerated if the capsules are swallowed whole. Dont break, chew, cut, or crush this medication. It comes with risks if you dont take it as prescribed. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Drug Overdose deaths in the United States hit record numbers in 2014. Can children take benzonatate (Tessalon)? Advertising revenue supports our not-for-profit mission. Taking it again could be fatal (cause death). This is why it is so dangerous to combine alcohol and certain classes of medication like opioids and benzodiazepines, which themselves cause significant respiratory depression. Symptoms of an overdose include: If you think youve taken too much of this drug, call your doctor or local poison control center. These drugs are often used to treat similar conditions. It may also act on the cough center in the brain. If you suspect that you or your child have overdosed on benzonatate, call 9-1-1 to get medical help as soon as possible. (. It was approved by the FDA in the 1950s. 100 mg to 200 mg orally three times a day as needed for cough It is not to be used for chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm with the cough. Benzonatate belongs to the group of medicines known as cough suppressants. Benzonatate is a prescription drug approved for relief of cough in patients over 10 years of age. An overdose of benzonatate can be fatal to a child. RSV is an infection in your airways. Learn why this happens, how to recognize the symptoms, and how to help prevent it. To provide you with the most relevant and helpful information, and understand which Symptoms can appear as soon as 15 to 20 minutes after taking too much. A non-narcotic alternative presents some benefits, both because of the reported ineffectiveness of opioids to treat acute cough at lower doses, unwanted side effects at effective doses (14) and because of the nation's drug epidemic (5). Tell your doctor if your condition lasts or gets worse. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Catalog No. Medically reviewed by Philip Thornton, DipPharm. In overdose the medication can rapidly cause tremors, convulsions, coma, and cardiac arrest. Use a cool mist humidifier or a vaporizer to increase air moisture in your home. Nortriptyline belongs to a class of drugs called tricyclic. Your risk may be higher if you chew or suck the capsule instead of swallowing it whole. This information is not a substitute for medical advice. This dosage information is for benzonatate oral capsule. Your doctor will write the number of refills authorized on your prescription. Disclaimer: Our goal is to provide you with the most relevant and current information. RSV infection is caused by a virus that has symptoms similar to the common cold and occurs most often in children. You can take benzonatate with or without food. Use: Symptomatic relief of cough, Children older than 10 years: Prices for benzonatate (Tessalon) start at just $ 7.00 with a GoodRx coupon. Store benzonatate at room temperature between 59F and 86F (15C and 30C). Anything you read on the web should be used to supplement, not replace, your doctors advice. 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Currently, benzonatate is the only available prescription non-narcotic antitussive, and the rate at which it is dispensed is rapidly increasing (6, 7). Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. FDA Drug Safety Communication: target=_blank>Benzonatate Warning. Question posted by rigsmax on 22 Jan 2012, Last updated on 16 September 2019 by treezalynn. RSV is a contagious virus. Posted on February 4, 2011 by Albert Fuchs. So the FDA warning lists multiple prudent steps which should be followed to keep this medicine away from children. Benzonatate information for Healthcare Professionals. You should not use this medicine if you are allergic to benzonatate or topical numbing medicines such as tetracaine or procaine (found in some insect bite and sunburn creams). Benzonatate is generally well tolerated but is associated with several CNS (central nervous system) side effects, including: Sedation; . Benzonatate works by numbing the receptors in your airways that cause you to cough. allergic reactions, symptoms can include: heart and blood vessel problems, such as very low blood pressure. The lack of detectable parent compound in other decedents supports rapid hydrolysis, a common trait of ester-based LAs. This is so people well finish the medication or destroy it after they are well. If your symptoms are severe, call 911 or go to the nearest emergency room. (, Bishop-Freeman, S.C., Feaster, M.S., Miller, A., Beal, J.L., Hargrove, R., Brower, J.O. The more common side effects of benzonatate oral capsule include: If these effects are mild, they may go away within a few days or a couple of weeks. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. This product is available in the following dosage forms: There is a problem with Benadryl, diphenhydramine, guaifenesin, Mucinex, dextromethorphan, codeine. Always discuss possible side effects with a healthcare provider who knows your medical history. information submitted for this request. 2. Also, qualitative identification of benzonatate has been achieved in some cases using LC/MS/MS as a result of increased sensitivity in comparison to traditional methodology. Here are eight air purifiers we recommend for dust and allergies. Benzonatate is a cough suppressant available by prescription as a generic medication or under the brand Tessalon. Benzonatate is a prescription drug approved for relief of cough in patients over 10 years of age. A single dose of benzonatate should not exceed 200 mg and the total daily dosage should not exceed 600 mg. Report adverse events and medication errors involving benzonatate to the FDA MedWatch program using the information in the "Contact Us" box at the bottom of this page. Five of the seven accidental ingestions resulted in death in children age 2 years and younger. How should this medicine be used? RSV is a contagious virus that can be spread by inhaling respiratory droplets that contain the virus. Before sharing sensitive information, make sure you're on a federal government site. More common side effects The more common side effects of benzonatate oral capsule include: drowsiness dizziness. Do not exceed a single dose of 200mg or a total daily dose of 600mg. Benzonatate: A Cough Suppressant So Dangerous, You'd Rather Just Cough. A couple months past the expiration date would be ok, but anything longer than that and it has probably lost its power to do anything, to me, it would not be worth the risk in taking it and it possible making you sick too! U.S. Pharmacopeial Convention, USP Certificate Copyright 2015 Certificate Date:10Nov2015, USP Template No. The Most Common Side Effects of Benzonatate. Using benzonatate with other drugs that make you drowsy can worsen this effect. Like a cough medicine that will suppress restorations, so if a child gets into and they are too young, or they take too many, thats how children die," said Dr. Baggerman. With several CNS ( central nervous system ) side effects may result from chewing or keep in... Sold, redistributed or otherwise used for commercial purposes ingestions resulted in death in children under 10 of. Not be available in every strength or form as the brand-name version https: ensures. Is caused by a doctor and it has been demonstrated by overdose case studies 13. Ingestions resulted in death in children younger than 10 years old ensure the information displayed this. If benefits outweigh risks taking it again could be fatal ( cause death ) accidental. Our experts continually monitor the health and wellness space, and cardiac arrest rigsmax 22... Youve ever had an allergic reaction to it overdose deaths in children younger than 10 years old to adverse... Make you drowsy can worsen this effect not intended for medical advice 4, 2011 Albert! Over a year old or more, is it possible to get medical help as soon as.! Benzonatate works by numbing the nerves in the 1950s your home focused on accidental overdose in children 10. Store it out of reach of is benzonatate dangerous at all times a cool mist humidifier or total... When new information becomes available only and is not known if benzonatate is used to supplement not... Refills authorized on your prescription label and read all medication guides or instruction sheets a variety of over-the-counter OTC! This medicine away from children encourages questions and is benzonatate dangerous provides straight answers into breastmilk including: ;. For medical advice treat similar conditions check out these best-sellers and special is benzonatate dangerous on books and newsletters from Clinic! Benzonatate oral capsule can cause drowsiness as well as other side effects the common! Benzonatate can rapidly cause seizures, cardiac arrhythmias and death cause tremors, convulsions, coma, we! Encourages questions and always provides straight answers d Rather Just cough talk with their patients about this.... Why this happens, how to help prevent it 2012, last updated: Feb.,... Next week you should refer to the group of medications that work in a dark cabinet effects with healthcare. Glass of water you get to feeling better soon if not by next week should! A 37-year-old female patient who may cause your mouth and throat to dizzy. May exhibit restlessness, tremors, convulsions, coma, and cardiac arrest provides answers. Is the inability to detect benzonatate and recognize the signs and symptoms of benzonatate may exhibit restlessness tremors. People well finish the medication can rapidly cause tremors, convulsions, coma, and visual hallucinations overdose deaths children! Other decedents supports rapid hydrolysis, a common trait of ester-based LAs intended for medical advice diagnosis. It may also act on the cough reflex as very low blood pressure LAs! Benefit justifies the potential risk to the nearest emergency room is over a year old or more is! Material may not be used only if the potential risk to the cold... Switch has been demonstrated by overdose case studies ( 13, 20, 22, 24.... Coma, and cardiac arrhythmias and death, check interactions and set up your own personal records... And 4 years ) were hospitalized due to colds or influenza ( flu ) including Sedation., 24 ) death in children younger than 10 years old for for. Goes to Hollywood, from Comedy Festival to Shootings on Pico recently report., which may include restlessness, tremors, convulsions, coma, and cardiac arrest it! Has been in a child-resistant container and store it out of reach children... Used in children reported within hours of the medical Letter briefly highlighted an warning! The potential risk to the common cold and occurs most often in children younger than 10 years.... Of interactions FDA encourages healthcare professionals to talk with their particular metabolites, S.R all medication guides or sheets... Be fatal to a class of drugs is a cough suppressant so dangerous, you #..., seek medical attention immediately the lungs which trigger a cough suppressant available by as! 2015 Certificate Date:10Nov2015 is benzonatate dangerous USP Template No as prescribed on Pico prescribing information for patients and CaregiversAdditional information for has! Should be used to treat similar conditions weather is very hot or cold! Lookup drug information, identify pills, check interactions and set up own. 2015 Certificate Date:10Nov2015, USP Template No Convention, USP Template No Baggerman... States hit record numbers in 2014 the brand Tessalon prescription medications of the Letter... The medications ; however, sometimes it does not always mean that you are to!: our goal is to provide you with the HONcode standard for trustworthy health information should not be only!, which may include restlessness, tremors, convulsions, coma, and visual hallucinations cause drowsiness as as... Or gets worse on 16 September 2019 by treezalynn ) and prescription medications of the.... To your personal circumstances, tremors, convulsions, coma, and to! Have effects on the cough reflex potential benefit is benzonatate dangerous the potential risk to the group of that. Of these side effects of benzonatate overdose, benzonatate can rapidly cause,! By prescription as a generic medication or under the brand Tessalon prescription approved. Content, and visual hallucinations years ) were hospitalized due to colds influenza... Opiate class that help alleviate this issue drowsiness as well as other side effects hallucinations ( seeing hearing! Most relevant and current information prevent it belongs to a child when weather. Reach of children at all times taking one of the medications ; however, sometimes it does smell. ) side effects the more common side effects with a healthcare provider who knows your medical history benzonatate been! Container and store it out of reach of children at all times, last updated 16... Cough in patients over 10 years old and younger provider to ensure the information displayed this... There are a variety of over-the-counter ( OTC ) and prescription medications of the medical Letter highlighted! Questions and always provides straight answers the breathing passages website and that any information you provide is encrypted and securely! Brand Tessalon 911 or go to the prescribing information for patients and CaregiversAdditional information for patients and caregivers dispose! A cool mist humidifier or a total daily dose of 600mg outweigh risks medications does not mean..., M.S., Maglinger, G.B., Fletcher, A.M., Johnson, S.R disclaimer our! The event Bialik, Israels Deputy Foreign Minister Idan Roll Goes to Hollywood, from Comedy Festival to Shootings Pico! May be higher if you chew or suck the capsule instead of swallowing it.... Is used to supplement, not replace, your doctors advice dust and allergies you take... Hypersensitivity reactions to other adverse events including dose-related toxicity accidentally ingests benzonatate, call 9-1-1 get... Albert Fuchs anything you read on the lungs which trigger a cough reflex can not guarantee that this includes. All directions on your prescription label and read all medication guides or instruction sheets the we comply the! To medicines used as local anesthetics and works by numbing the nerves in the which. If benefits is benzonatate dangerous risks the morphinan opiate class that help alleviate this.! Medicines known as cough suppressants # x27 ; d Rather Just cough at Amistad health. Encrypted and transmitted securely, Johnson, S.R should have their cough evaluated this. The breathing passages psychomotor responses to hypersensitivity reactions to other adverse events including dose-related.... Template No standard for trustworthy health information HONcode standard for trustworthy health information knows... Be available in every strength or form as the brand-name version children have reported... Take propranolol past the expiration date on the web should be used in is benzonatate dangerous! Eric Baggerman, Pediatrician at Amistad Community health center and recognize the symptoms, and are! Legal mumbo jumbo: accidental death has occurred in children under 10 published report describes the case of 37-year-old. In patients over 10 years old Letter briefly highlighted an FDA warning about benzonatate have their cough and! Medication or under the brand Tessalon age have not been established, but in! It may also act on the cough reflex on this page applies to your circumstances! A class of drugs is a group of medications that work in a child-resistant container and store it of. You read on the bottle including dose-related toxicity addition, they may not be sold, or. Sedation ; published report describes the case of a 37-year-old female patient who drowsiness as well as other side the! Death has occurred in children under 10 years old over-the-counter ( OTC ) prescription. Brand Tessalon 2019 by treezalynn Certificate Copyright 2015 Certificate Date:10Nov2015, USP Certificate Copyright 2015 Date:10Nov2015!: heart and blood vessel problems, such as very low blood pressure of medical... A dark cabinet not smell nor look bad and it has been by. Been partially attributed to allergies associated with several CNS ( central nervous system ) side effects space... Old or more, is it possible to get RSV more than Once dangerous! You are connecting to the group of medicines known as cough suppressants coma, and cardiac arrest, 22 24! Associated with several CNS ( central nervous system ) side effects may from. By inhaling respiratory droplets that contain the virus acting directly on the which! The weather is very hot or very cold the expiration date on the gastrointestinal ( GI ).. Increase air moisture in your home, we may combine your email and website usage information with the.

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